It follows their narrow 20 -24 defeat by the Leicester Tigers last Saturday.
Phil Dollman and Jack Nowell both return for the first time this season, taking over from Ceri Sweeney and Jack Arnott.
Two changes have been made to the starting line-up with Ben Moon coming in for Carl Rimmer, while Damian Welch comes in instead of Ryan Caldwell.
Raw sewage spews into Plymouth suburb estate and woods
Councillor stands under trees to stop chainsaw massacre
Three years jail for charity box thief
Spat over whether 'inadequate' children's services are as bad as MP suggests
Totnes market not opening in Christmas week
