The centre in Sidwell Street s the subject of a review which also includes out-of hours services and minor injuries units.
Campaigners are preparing to present a petition to the local Clinical Commissioning Group next week.
There's a proposal for Exeter to have one or more urgent care centres providing these services, and various organisations are bidding for the contract.
“Disappointment” over North Devon funding settlement
Controversial Exeter road consultation to begin in the New Year
Exeter care agency rated 'inadequate' and in special measures
Raw sewage spews into Plymouth suburb estate and woods
Councillor stands under trees to stop chainsaw massacre
