Nine hundred new homes and community facilities could be built near Exeter Science Park.
The plans have been submitted to East Devon district council and include more than 250 affordable homes, as well as a health centre, primary school, shops and a cafe, and sports facilities.
The site is bounded by the River Clyst, the railway and the A30.
Two men missing after entering sea
Huge emergency response in Budleigh Salterton
Students take over Radio Exe
Christmas Day special from Xpression FM
Work to start on major Tavistock Road improvements
£45 million scheme moves to phase 2
Last night of the Christmas Proms - REVIEW
Bournemouth Symphony Orchestra at the Great Hall
Christmas snow possible on Dartmoor
That's despite no white-Christmas predicted
Car thug sought
This man may be able to help enquiries
